Table 1.
Demographics of the participants (n = 322).
| HC (CDR of 0) | MCI (CDR of 0.5) | p-value | |
|---|---|---|---|
| Number | 136 | 186 | |
| Age, y | 78 (76–81)b | 80 (76–83)b | <0.005 |
| Gender, M/F | 55/81 | 84/102 | 0.40 |
| Education, y | 9 (8–11)a | 8 (8–9)a | 0.01 |
| MMSE | 26 (24–27)c | 23 (21–25)c | <0.001 |
| WMS-R LMII | 9 (5–13)c | 4 (1–10)c | <0.001 |
| GDS-15 | 3.5 (2–6) | 4 (2–7) | 0.07 |
| WMHr, % | 1.03 (0.54–1.82)c | 1.76 (0.87–3.06)c | <0.001 |
Data are presented as numbers or medians (interquartile ranges). Abbreviations: CDR = Clinical Dementia Rating; F = female; HC = healthy elderly control; GDS-15 = 15-item Geriatric Depression Scale; M = male; MCI = mild cognitive impairment; WMHr = cerebral white matter hyperintensity volume as a percentage of the total intracranial volume; WMS-R LMII = Wechsler Memory Scale-Revised Logical Memory II. ap < 0.05, bp < 0.005, cp < 0.001.