Table 5. Upregulated Antisense Transcripts (382).
N | LOD | P | P_adj | attrib ID | attrib name |
---|---|---|---|---|---|
9 | 1.570899749 | 7.66E-10 | 0 | GO:0005353 | Fructose transmembrane transporter activity |
9 | 1.570899749 | 7.66E-10 | 0 | GO:0015578 | Mannose transmembrane transporter activity |
9 | 1.508665946 | 1.69E-09 | 0 | GO:0005355 | Glucose transmembrane transporter activity |
9 | 1.454222369 | 3.47E-09 | 0 | GO:0015145 | Monosaccharide transmembrane transporter activity |
9 | 1.454222369 | 3.47E-09 | 0 | GO:0015149 | Hexose transmembrane transporter activity |
11 | 1.340249894 | 4.22E-10 | 0 | GO:0051119 | Sugar transmembrane transporter activity |
10 | 1.298536807 | 5.17E-09 | 0 | GO:0008645 | Hexose transport |
10 | 1.298536807 | 5.17E-09 | 0 | GO:0015749 | Monosaccharide transport |
11 | 1.180032699 | 7.49E-09 | 0 | GO:0015144 | Carbohydrate transmembrane transporter activity |
13 | 1.031860845 | 9.38E-09 | 0 | GO:0008643 | Carbohydrate transport |
36 | 0.41867088 | 3.33E-06 | 0.047 | GO:0022891 | Substrate-specific trans-membrane transporter activity |
GO term enrichment reveals an overrepresentation of antisense hexose transporter transcripts in DBP2-deficient cells. Genes with overlapping, antisense transcripts that were significantly overrepresented in dbp2∆ cells as compared to wild type were selected from the RNA sequencing data set. GO term analysis was conducted using FuncAssociate 2.0 as above. The columns are as follows: N, no. of entries in the category; LOD, Log10 of the odds ratio; P, one-sided P-value of the association of attribute and query; P_adj, adjusted P-value as a fraction of 1000 null-hypothesis simulations; attrib ID, GO term 8 identification number for attribution category; attrib name, category name for functional processes.