Table 3. Activation of network modules and enrichment of known genes relevant to liver fibrosis.

Module	Activation score in Liver fibrosis	No. of genes in module	No. of fibrosis genes (set 1)a	p-value (set 1)a	No. of cirrhosis genes (set 2)b	p-value (set 2)b
M1	1.47	150	1	0.24	1	1
M2	0.95	144	3	0.002	5	0.003
M3	1.67	127	2	0.02	0	1
M4	1.92	110	1	0.18	1	0.52
M5	2.12	92	6	1.28E-08	13	3.25E-14
M6	0.77	81	1	0.14	2	0.10
M7	1.09	58	-	1	1	0.32
M8	1.38	49	-	1	2	0.04
M9	0.36	46	-	1	1	0.27
M10	0.87	40	-	1	1	0.24
M11	1.38	34	-	1	1	0.20

^aLiver fibrosis-relevant genes collected from literature [3], [5], [55], [56]

^bLiver cirrhosis-relevant genes collected from the Comparative Toxicogenomics Database (CTD)