Figure 3.

DNA damage repair pathway responses profiles reveal distinct potential DNA damage mechanisms among different ENMs. The mean natural log value of TELI_pathway or PELI_pathway indicates the magnitude of pathway responses (represented by a black–red color scale at bottom. Values over 1.5 are shown as 1.5). MMC: mitomycin C; CB: carbon black; SWCNT: single wall carbon nanotube; C60: purified fullerene; BPA: bisphenol A. X-axis top: pathways of DNA damage repair (see Table 1 for details). Y-axis left: chemical/ENM and concentration(s) from lowest to highest from top to bottom (see concentrations in SI Table S1).