Table 1. Demographic data, clinical characteristics, and underlying conditions of 82 patients with an invasive H. influenzae episode during the period 2008–2013.
| Patients (n = 82) | |
| Characteristics [no. (%)] | |
| Age (mean ± SD); range | 64.3±16.1; 21–96 |
| Male sex | 52 (63.4) |
| Acquisition | |
| Community-acquired | 71 (86.6) |
| Hospital-acquired | 11 (13.4) |
| Source of infection | |
| Pneumonia/empyema | 49 (59.8) |
| Meningitis | 9 (11.0) |
| Biliary tract infection | 9 (11.0) |
| Primary bacteremia | 7 (8.5) |
| Epiglottitis | 2 (2.4) |
| Othersa | 6 (7.3) |
| Underlying conditions [no. (%)] | |
| Immunosuppressive therapy | 28 (34.1) |
| Solid organ malignancy | 26 (31.7) |
| Diabetes | 18 (22.0) |
| COPD | 18 (22.0) |
| Heart disease | 15 (18.3) |
| Chronic liver disease | 11 (13.4) |
| Hematologic malignancyb | 9 (11.0) |
| Cerebrovascular disease | 5 (6.1) |
| Organ transplantc | 4 (4.9) |
| HIV | 2 (2.4) |
| Othersd | 10 (12.2) |
| Shock | 18 (22.0) |
| Neutropenia | 8 (9.8) |
| Mortality | |
| <30 days | 17 (20.7) |
a
Facial cellulites, endometritis, liver abscess, and urinary-tract infection (n = 1, 1.2% each), and peritonitis (n = 2, 2.4%).
b
Leukemia (n = 3, 3.6%), lymphoma (n = 1, 1.2%), and myeloma (n = 5, 6.1%).
c
Bone marrow transplant (n = 1, 1.2%), kidney transplant (n = 1, 1.2%), and liver transplantation (n = 2, 2.4%).
d
Cerebrospinal fluid fistula (n = 2, 2.4%), renal failure, autoimmune disease, and head trauma (n = 1, 1.2% each).