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Representative PET images of INS-1 tumor mice at 1 (a) and 2 h (b) postinjection of [18F]FNEM-[Cys40]-exendin-4 (30 μCi) for the control and blocking groups (n = 5/group). (c) Quantification of tumor uptake at 1 and 2 h postinjection. (d) Direct tissue sampling measurement of the biodistribution of [18F]FNEM-[Cys40]-exendin-4 right after the PET acquisition at 2 h time point.
