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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Osteoporos Int. 2014 Aug 20;25(12):2673–2684. doi: 10.1007/s00198-014-2783-5

Table 1. Mode of presentation in children with rickets in case series published since 2000.

Study Country Time period of study Number of children Age range Presenting feature, n (%)
Fracture Skeletal Deformity Hypocalcaemic Seizure
Agarwal, 2009[112] India 2006-2008 51 10-13y 3 (5.9) 19 (37.3) 0 (0.0)
Ahmed, 2010[3] UK 2002-2008 160 2w-14y 11 (6.9) 64 (40.0) 19 (11.9)
Al-Atawi, 2009[45] Saudi Arabia 1990-2000 283 6-14m 4 (1.4) NR 98 (40.3)
Al-Jurayyan, 2002[46] Saudi Arabia 1994-1999 42 6-18y 3 (7.1) 5 (11.9) NR
Beck-Nielsen, 2009[47] Denmark 1985-2005 112 0-15y 5 (4.5) NR 15 (13.4)
Blok, 2000[44] New Zealand 1998 18 3-36m 1 (5.6) 7 (53.8) 3 (16.7)
Chapman, 2010[49] USA 2000-2007 32 2-24m 7 (21.9) NR NR
Hatun, 2005[113] Turkey 2001-2003 47 0-3m 0 (0.0) 0 (0.0) 33 (78.7)
Lazol, 2008[6] USA 1995-2005 58 2-132m 9 (15.5) 23 (39.7) 7 (12.1)
Miyako, 2005[48] Japan 1992-2001 10 2-31m 2 (20.0) 7 (70.0) 2 (20.0)
Mylott, 2004[43] USA 1996-2004 51 4-24m 5 (9.8) 14 (27.4) 5 (9.8)
Narchi, 2001[114] Saudi Arabia 1996-1997 21 11-15y 0 (0.0) 2 (9.5) NR
Pedersen, 2003[51] Denmark 1990-1999 40 6m-15y 5 (12.5) 17 (42.5) 2 (5.0)
Robinson, 2006[4] Australia 1993-2003 126 0-15y 5 (4.0) 28 (22.2) 42 (33.3)
Thacher, 2013[5] USA 1970-2009 17 0-3y 0 (0.0) 8 (47.1) 2 (11.8)
Tomaschek, 2001[115] Georgia 1997-1999 5 8-21m 0 (0.0) 0 (0.0) 2 (40.0)
Ward, 2007[22] Canada 2002-2004 104 0-7y 11 (10.6) 44 (42.3) 20 (19.2)

ALL STUDIES 1177 71 (6.0) 238 (31.7) a 250 (23.1) a

NR – not reported

(a) Percentage calculated from studies in which mode of presentation was reported