Extended Data Figure 9. Autologous virus Env sequence and the impact of variants on 35O22 neutralization.
a, A total of 12 single-genome amplicons from plasma of patient N152 were sequenced. Donor Env sequences together with the reference sequences of JRCSF and LAI are aligned. Amino acids critical for 35O22 neutralization of JRCSF and LAI are labeled in yellow. Differences between autologous and JRCSF sequences are labeled in green. b, 35O22 neutralization of JRCSF pseudovirus or variants containing the autologous virus mutations from patient N152. Error bars denote one standard error of the mean.