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Hypothermic effects of nicotine, varenicline, and cytisine alone and in combination with mecamylamine (left) or DHβE (right). Abscissae: dose of nicotine, varenicline, or cytisine in milligram per kilogram body weight. Ordinates: the area calculated from the hypothermia time course in Figure 3 and expressed as a percentage of the maximum effect for each respective drug.
