Table 3.
List of well known medicines that may cause anticholinergic syndrome in human beings, particularly after overdose
| Drug class | Drug |
|---|---|
| Antihistamines | Azatadine (Opimine), bromopheniramine (Dimetane®, Dimetap), chlorpheniramine (Chlor-Trimeton, Contac, Deconamine, Histussin, Naldecon, Tiraminic), clemestine (Tavist), carbinoxamine (Rondec), cyproheptadine (Periactin), dimenhydrinate (Dramaine), diphenhydramine (Benadryl®), hydroxyzine (Atarax, Vistaril), loratadine (Claritin, Reditabs), promethazine (Phenergan), pyrilamine (Triaminic), triprolidine (Actifed, Allercon) |
| Antiparkinsonim | Amantadine (Symmetrel), benzotropine (Cogentin), orphenadrine, trihexyphenidyl hydrochloride (Artane) |
| Antipsychotics | Chlorpromazine (Thorazine), droperidol (Inapsine), fluphenazine (Prolixin), haloperidol (Haldol), loxapine (Loxitane), mesoridazine (Serentil), molindone (Moban), perphenazine (Trilafon), pimozide (Orap), thioridazine (Mellaril®), trifluoperazine (Stelazine®), thiothixene (Navane)Antispasmodics (Gastrointestinal) Atropine, belladonna (Bellergal-S®), clindium bromide, dicyclomine hydrochloride (Bentyl®), Donnatol® (phenobarbital, atropine, hyoscyamine, scopolamine), glycopyrrolate (Robinul®), hyoscyamine (Levsin) |
| Antispasmodics (Genitourinary) | Flavoxate hydrochloride (Urispas®), Oxybutynin chloride (Ditropan®), Tolterodine (Detrol) |
| Bronchodilators | Ipratropium bromide (Atrovent) |
| Carbamazepine (Tegretol) | Carbamazepine |
| Motion-sickness Medications | Scopolamine, Meclizine (Antivert) |
| Mushrooms | Amanita species including muscaria, gemmata and pantherina Many other mushrooms species |
| Ophthalmic Cycloplegics | Cyclopentolate (Cyclogyl®), Homatropinehydrobromide, Tropicamide (Mydriacyl |
| Skeletal Muscle Relaxants (central acting) | Methocarbamol, , Metoxalen |
| Cyclic antidepressants | Amitriptyline ,Amitriptylinoxide, Butriptyline, Clomipramine , Demexiptiline, Desipramine, Dibenzepin, Dimetacrine, Dosulepin/Dothiepin ,Doxepin ,Imipramine, Imipraminoxide, Lofepramine, Melitracen, Metapramine, Nitroxazepine, Nortriptyline, Noxiptiline, Pipofezine, Propizepine, Protriptyline, Quinupramine |
| Others | Promethazine (Phenergan®) Cyclobenzaprine (Flexeril®), Orphenadrine (Norflex®) |