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Pharmacokinetic parameters and statistical comparisons
| With DCV | W/O DCV | GMR | ||
|---|---|---|---|---|
| Adj. Geo. Mean | Adj. Geo. Mean | (90% CI) | ||
| R-METa | Cmax, ng/mL | 103.6 | 96.6 | 1.07 (0.97, 1.18) |
| AUCTAU, ng•h/mL | 1699.6 | 1569.8 | 1.08 (0.94, 1.24) | |
| BUP | Cmax, ng/mL | 3.3 | 2.5 | 1.30 (1.03, 1.64) |
| AUCTAU, ng•h/mL | 25.1 | 19.2 | 1.31 (1.15, 1.48) | |
| NORBUP | Cmax, ng/mL | 3.1 | 1.8 | 1.65 (1.38, 1.99) |
| AUCTAU, ng•h/mL | 42.6 | 26.4 | 1.62 (1.33, 1.96) | |
