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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Obesity (Silver Spring). 2014 Aug 20;22(11):2396–2405. doi: 10.1002/oby.20879

Fig. 5.

Fig. 5

Attenuation of isoflurane post-treatment-induced neuroprotection by inhibition of Akt activation. Hippocampal slices were freshly prepared from 16-week old CD-1 mice that fed HFD or RD for 10 weeks. The slices were subjected to a 20-min OGD and then exposed to 3% isoflurane for 30 min. LY 294002 (LY) was presented from the beginning of OGD to the end of isoflurane exposure. PI staining was performed at 5 h after the OGD. A: representative images of PI staining. B: data of RD-fed mice. C: data of HFD-fed mice. Results are mean ± S.E.M. (n = 5). * P < 0.05 compared with control; ^ P < 0.05 compared with OGD.