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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: J Endocrinol. 2014 Oct 6;223(3):277–287. doi: 10.1530/JOE-14-0509

Fig.2.

Fig.2

Tissue distribution and expression of RNase L The expression of RNase L in the tissue extracts from eight organs (A) and several types of cells (B). Sp-cells: primary splenocytes; BMM: bone marrow-derived macrophages; NIH3T3: mouse fibroblasts; MEF: mouse embryonic fibroblasts. (C) IFN-α induces the expression of RNase L in NIT-1 cells NIT-1 cells were treated with 1,000 units/ml of IFN-α (R&D Systems) for 16 h and RNase L in the cells was determined by Western blot analysis. (D) Mice (2/group) were treated with or without poly I:C at a concentration of 5 μg/g body weight every other days for one week (three times) and the level of RNase L in the pancreatic tissue extract was determined by Western blot analysis with a polyclonal antibody to mouse RNase L.