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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: J Endocrinol. 2014 Oct 6;223(3):277–287. doi: 10.1530/JOE-14-0509

Fig. 3.

Fig. 3

Effect of RNase L on STZ and poly I:C - induced Diabetes A. Genotyp ing of B7.1 - RL−/− mice. B. Incidence of diabetes in RNase L (RL)+/+ and −/− (n=10 for each group), B7.1-RL+/+ (n=8) and B7.1-RL−/− (n=9) mice after injection with 40mg/kg STZ for five consecutive days. C. Incidence of diabetes in B7.1-RL+/+ (n=9) and B7.1-RL−/− (n=8) mice after injected (i.p.) with 5 μg/g body weight poly I:C daily for 7 days, and then injected (i.p.) with 25 μg/mouse of insulin on day 14 after poly I:C treatment . The glucose levels in t he blood samples were measured by using a blood sugar test kit (Pointe Scientific). The mice were considered diabetic after two consecutive blood glucose values ≥ 250 mg/dl.