Table 3.
Expression of mRNA analyzed by REST software
|
TNF-
|
|
IL-12
|
|
IL-10
|
|
IL-4
|
Group | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Result | P(H1) | Exp | Result | P(H1) | Exp | Result | P(H1) | Exp | Result | P(H1) | Exp | ||||
| 0.091 | 1.583 | UP | 0.012 | 2.497 | 0.245 | 1.619 | 0.228 | 1.439 | Brain Q10-EAE + CoQ10 | ||||||
| UP | 0.004 | 6.052 | UP | 0.023 | 2.387 | DOWN | 0.045 | 0.589 | 0.682 | 0.831 | Brain control- EAE | ||||
| 0.317 | 1.31 | UP | 0 | 2.334 | UP | 0.01 | 1.803 | 0.056 | 2.136 | Brain control-EAE + sesame oil | |||||
| 0.056 | 1.561 | 0.862 | 1.037 | 0.121 | 2.014 | 0.566 | 0.831 | Brain control-EAE + CoQ10 | |||||||
| DOWN | 0.018 | 0.258 | UP | 0.016 | 0.435 | UP | 0.034 | 3.416 | 0.976 | 1.000 | Brain EAE- EAE + CoQ10 | ||||
| DOWN | 0 | 0.217 | 0.914 | 0.978 | UP | 0.01 | 3.058 | UP | 0.041 | 2.571 | Brain EAE- EAE + sesame oil | ||||
| 0.189 | 1.556 | UP | 0.018 | 2.301 | 0.59 | 0.782 | 0.877 | 1.063 | Brain oil-EAE + sesame oil | ||||||
Exp is related to mRNA expression, P(H1) shows Pv, and Result is correlated with decrease or increase in gene expression. UP, up-regulation; DOWN, down-regulation