Table 1.
Cohort characteristics
| Crohn’s disease (n = 697) |
Ulcerative colitis (n = 408) |
|
|---|---|---|
| Median age at diagnosis (IQR) (in years) |
24 (18 – 33) | 27 (21 – 38) |
| Male sex | 324 (46) | 196 (48) |
| Median disease duration (IQR) (in years) |
10 (5 – 18) | 8 (4 – 16) |
| Family history of IBD | 188 (27) | 85 (21) |
| ≥ 2 first degree relatives with IBD |
36 (5) | 21 (5) |
| Disease behavior | ||
| Inflammatory | 319 (48) | |
| Stricturing | 150 (22) | |
| Penetrating | 207 (31) | |
| Disease location | ||
| Ileal | 151 (22) | |
| Colonic | 176 (26) | |
| Ileocolonic | 355 (52) | |
| Perianal disease | 194 (28) | |
| Disease extent | ||
| Proctitis | 44 (11) | |
| Limited colitis | 133 (34) | |
| Pancolitis | 214 (55) | |
| Immunomodulators | 503 (72) | 237 (58) |
| Biologic anti-TNFs | 392 (56) | 133 (33) |
| Bowel Resection | 304 (44) | 37 (9) |
| Smoking | ||
| Never | 421 (62) | 251 (64) |
| Former | 203 (30) | 125 (32) |
| Current | 53 (8) | 17 (4) |
TNF – tumor necrosis factor