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Cathelicidins do not protect macrophages from anthrax LeTx-induced cytolysis. RAW 264.7 cells were incubated for 5 h with PBS or serially diluted HNP-1 (A), PG-1 (B), CRAMP (C), or LL-37 (D) with low or high levels of LeTx (400 ng/ml lethal factor and 200 ng/ml or 1600 ng/ml protective Ag, respectively). Cell viability was determined by alamarBlue reduction. Points represent the mean values pooled from three experiments conducted in duplicate ± SEM.
