Table 2. Central field focal-ERG A- and B-wave amplitudes in Pde6brd10/rd10 mice under systemic VPA-treatment (age P17-P28, late dosing), measured at age P25.
Group |
B-wave |
A-wave |
---|---|---|
(µV ± SD) | (µV ± SD) | |
VPA (n=3) |
119±18.2 |
−13.3±5.7 |
PBS (n=2) |
140±17.0 |
−25.0±7.1 |
P value (t test) | 0.14 | 0.06 |
Focal-ERG tests were completed at age P25. Mixed rod-cone responses of dark-adapted retinas, using a circular bright light flash stimulus of 6 optic disc diameters, centered on the optic disc.