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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Pharm Res. 2014 May 30;31(12):3379–3389. doi: 10.1007/s11095-014-1427-y

Table II.

Loading efficiencies of microparticle formulations.

Loading Efficiency of 10 wt% antibiotic-loaded PLGA MPs (%) Loading Efficiency of 20 wt% antibiotic-loaded PLGA MPs (%)
Cefazolin 36.4 ± 3.3a 51.3 ± 6.1d
Ciprofloxacin 86.8 ± 10.9b,c,* 38.9 ± 17.8d,*
Clindamycin 84.9 ± 6.9b,c 89.5 ± 4.0e,f
Colistin 102.0 ± 5.0c 105.3 ± 4.4f
Doxycyline 71.4 ± 2.3b 89.4 ± 0.9e,f
Vancomycin 83.3 ± 4.8b,c 76.9 ± 6.2e
*

Indicates significant difference between 10wt% and 20wt% loaded for a given antibiotic.

Superscript letters indicate significant difference between antibiotics for a given loading wt%

Data is presented as mean ± standard deviation, n=3 per group.