Table II.
Loading Efficiency of 10 wt% antibiotic-loaded PLGA MPs (%) | Loading Efficiency of 20 wt% antibiotic-loaded PLGA MPs (%) | |
---|---|---|
Cefazolin | 36.4 ± 3.3a | 51.3 ± 6.1d |
Ciprofloxacin | 86.8 ± 10.9b,c,* | 38.9 ± 17.8d,* |
Clindamycin | 84.9 ± 6.9b,c | 89.5 ± 4.0e,f |
Colistin | 102.0 ± 5.0c | 105.3 ± 4.4f |
Doxycyline | 71.4 ± 2.3b | 89.4 ± 0.9e,f |
Vancomycin | 83.3 ± 4.8b,c | 76.9 ± 6.2e |
Indicates significant difference between 10wt% and 20wt% loaded for a given antibiotic.
Superscript letters indicate significant difference between antibiotics for a given loading wt%
Data is presented as mean ± standard deviation, n=3 per group.