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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Pharm Res. 2014 May 30;31(12):3379–3389. doi: 10.1007/s11095-014-1427-y

Table IV.

Correlation coefficients between physicochemical properties and loading efficiency, dominant rate of release, and length of lag phase.

Charge Molecular Weight logP logS
Loading Efficiency 10 wt% 0.82 0.39 −0.20 −0.13
Loading Efficiency 20 wt% 0.68 0.45 −0.05 −0.34
Release Rate 10 wt% −0.15 −0.14 −0.02 −0.03
Release Rate 20 wt% −0.26 −0.19 −0.47 −0.18
Length of Lag Phase 10 wt% 0.64 0.85 −0.57 −0.75
Length of Lag Phase 20 wt% 0.55 0.93 −0.68 −0.86