Figure 6.
Spatial Organization of Neocortical Excitatory Neuron Clones
(A) 3D reconstruction images of representative clones that are “cone” shaped (left) and “cylinder” shaped (right) at P7–P10 (top) and P21–P30 (bottom) labeled at E10–E12.
(B) Quantification of the ratio of the maximal lateral dispersion in the superficial layer 2/3 in all dimensions (d2) to that in the deep layer 6 (d1) (see A) for clones located in different regions of the neocortex (medial [M], n = 19; dorsal [D], n = 33; lateral [L], n = 16; see inset at the bottom). Individual circles represent a single clone. Mean and SEM are shown in red (∗p < 0.05 and ∗∗p < 0.01; n.s., not significant).
(C and D) No correlation between the clone shape and the clone size (C) or the ratio of neuron number in the superficial (2–4) and deep (5–6) layers (D). Each dot indicates a clone and black lines indicate mean ± SEM.