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Summary of equilibrium and apparent kinetic constants
| Immobilized protein | Analyte | ka (×105), M−1 S−1 | kd (×10−4), S−1 | KD, nM |
|---|---|---|---|---|
| Human CD40 | ASKP1240 | 1.22 ± 0.12 | 0.29 ± 0.01 | 0.24 ± 0.02 |
| Monkey CD40 | ASKP1240 | 1.26 ± 0.03 | 0.36 ± 0.03 | 0.28 ± 0.03 |
| Rabbit CD40 | ASKP1240 | 1.32 ± 0.03 | 1.90 ± 0.33 | 1.44 ± 0.26 |
ka, association constant; kd; dissociation constant; KD, equilibrium dissociation constant.
The mean ± SD of three independent experiments is shown.
