Table 4.
Efficacy of AED regimen (n = 854)
| AED regimen | Retention rate At the end of F/U (%/ number of patients) | P value | Seizure free At the end of F/U (%/ Number of patients) | P value |
|---|---|---|---|---|
| CBZ |
91 (287/318) |
|
96 (275/287) |
|
| VPA |
86 (154/179) |
|
95 (146/154) |
|
| PHB |
22 (15/ 68) |
|
98 (14/15) |
|
| PHT |
29 (5/ 17) |
|
100 (5/5) |
|
| CBZ + VPA |
100 (115/115) |
|
96 (110/115) |
|
| CBZ + PHB |
88 (30/34) |
<0.001 |
90 (27/30) |
<0.001 |
| CBZ + PHT |
65 (17/26) |
|
76 (13/17) |
|
| VPA + PHB |
77 (16/21) |
|
88 (14/16) |
|
| CBZ + VPA + PHT |
100 (34/34) |
|
88 (30/34) |
|
| CBZ + PHB + PHT |
92 (24/26) |
|
75 (18/24) |
|
| CBZ + VPA + TOP |
100 (8/8) |
|
88 (7/8) |
|
| CBZ + VPA + LTG | 100 (8/8) | 88 (7/8) |
PHB = Phenobarbitone, CBZ = Carbamazepine, VPA = Sodium Valproate, PHT = Phenytoine, TOP = Topiramate, LTG = Lemotrigine.