Figure 5.

Hierarchical Analysis of Functional Enrichment

DHS variants were further partitioned into three subcategories: predicted enhancers (A), cell-type-specific DHSs (B), and DGF targets (C). Each block contains (on the top line) the functional category and fraction of the genome (in parentheses) and (on the bottom line) the fraction enriched in relation to the rest of the genome and the p value of enrichment in relation to the parent category (in parentheses). DHS enrichment of 4.7× nonsignificantly differed from 5.1× in Figure 3 as a result of additional free parameters.