Table 2.
Variant Class | Percentage of | |
---|---|---|
Separately | ||
All | 0.370 ± 0.040 | – |
Noncoding | 0.317 ± 0.042 | – |
Coding | 0.158 ± 0.034 | – |
Jointly | ||
Noncoding | 0.291 ± 0.028 | 79% ± 8% |
Coding | 0.079 ± 0.034 (p = 1.2 × 10−2) | 21% ± 6% |
Coding (rare) | 0.037 ± 0.029 (p = 1.0 × 10−1) | 10% ± 7% |
Coding (common) | 0.042 ± 0.017 (p = 7.7 × 10−3) | 11% ± 4% |
Estimates of (adjusted for biases due to LD; see Figure S17 and Table S23) are reported from variance components in the homogenous Swedish subpopulation. The top section shows estimates that include tagging of variants in other classes. The bottom section shows joint estimates accounting for tagged variance due to LD. The p values from a likelihood-ratio test are shown in parentheses.