Table 1.

Summary of key drug-drug interactions between HIV drugs and the licensed DAAs and dosing recommendations

	Telaprevir	Boceprevir
ATV/r	Monitoring for hyperbilirubinemia recommended	Consider on a case by case basis if deemed necessary
DRV/r/, FPV/r LPV/r	Not recommended	Not recommended
EFV	Increase TVR to 1,250 mg q8h	Not recommended
ETR	No dose adjustment needed	No dose adjustment needed
RPV	No dose adjustment needed	No dose adjustment needed
RAL	No dose adjustment needed	No dose adjustment needed
TDF	Increased monitoring is warranted	No dose adjustment needed