Table 1.
General characteristics of 166 patients with infective endocarditis (IE)
| |
No. (%) of patients |
p | |||
|---|---|---|---|---|---|
| Characteristic |
TOTAL |
Native valve |
Prosthetic valve |
||
| (189 events, 166 patients) | (118 events, 111 patients) | (71 events, 55 patients) | |||
|
Age (years), median [IQR] |
57 [43–72] |
53 [42–71] |
66 [50–75] |
0.01 |
|
|
Male gender |
104 (63%) |
72 (65%) |
32 (58%) |
0.4 |
|
|
Time from onset of symptoms to admission |
|
||||
| |
< 7 days |
69 (37%) |
41 (35%) |
28 (39%) |
|
| |
>7 and ≤21 days |
42 (22%) |
25 (21%) |
17 (24%) |
|
| |
> 21 days |
55 (29%) |
34 (29%) |
21 (30%) |
1 |
| |
NA |
23 (12%) |
18 (15%) |
5 (7%) |
|
|
Co-morbidities |
|
||||
| |
Cancer |
14 (7%) |
13 (11%) |
1 (1%) |
0.01 |
| |
Hypertension |
39 (21%) |
21 (18%) |
18 (25%) |
0.2 |
| |
Acute/chronic renal failure |
17 (9%) |
6 (5%) |
11 (15%) |
0.02 |
| |
Ischemic cardiopathy |
21 (11%) |
9 (8%) |
12 (17%) |
0.05 |
| |
Diabetes mellitus |
29 (15%) |
17 (14%) |
12 (17%) |
0.6 |
| |
COPD |
9 (5%) |
4 (3%) |
5 (7%) |
0.2 |
| |
CLD |
55 (29%) |
41 (35%) |
14 (20%) |
0.03 |
| |
HIV infection |
35 (19%) |
27 (23%) |
8 (11%) |
0.05 |
| |
CD4 cells/μL [IQR] |
268 [145–353] |
248 [124–313] |
447 [348–1814] |
0.008 |
| |
HIV-RNA cp/mL (n 22) |
|
|
|
|
| |
<10000 |
14 (40%) |
8 (30%) |
6 (75%) |
|
| |
10000-100000 |
5 (14%) |
4 (15%) |
1 (13%) |
0.11 |
| |
>100000 |
4 (11%) |
4 (15%) |
0 |
|
| |
NA |
12 (34%) |
11 (41%) |
1 (13%) |
|
| |
HAART at IE |
|
|
|
|
| |
No |
21 (60%) |
15 (56%) |
6 (75%) |
0.2 |
| |
Yes |
14 (40%) |
12 (44%) |
2 (25%) |
|
| Data are median [interquartile range] or numbers (%). | |||||
NA, Not available; COPD, Chronic obstructive pulmonary disease; CLD, Chronic liver disease; HAART, Highly active antiretroviral therapy.