Table 4.

Results of multivariable regression modeling of associations with in-hospital death

VARIABLE	AOR (95% CI)	p value
Age in 10 y intervals	1.26 (0.95-1.69)	0.1
Female sex	0.60 (0.20-1.78)	0.4
PVE early recurrence	0.88 (0.30-2.59)	0.8
PVE late recurrence	2.12 (0.80-5.58)	0.1
Intravenous drug use	0.60 (0.14-2.57)	0.5
Health care associated IE	3.35 (1.27-8.78)	0.01
CoNS – associated IE	0.50 (0.09-2.78)	0.4
Staphylococcus aureus	3.83 (0.95-15.44)	0.058
Viridans group streptococci	1.26 (0.33-4.77)	0.7
Others*	1.98 (0.58-6.80)	0.3
Mitral valve involvement	1.33 (0.53-3.30)	0.5
Complications**	5.58 (1.79-17.31)	0.003
Surgery	0.38 (0.16-0.94)	0.04

CoNS, Coagulase-negative staphilococci; MSSA, Methicillin-sensitive Staphylococcus aureus; MRSA, Methicillin-resistant Staphylococcus aureus; PVE, prosthetic valve endocarditis.

*Others: Enterococcus spp, Fungi/Yeast, Gram-negative bacteria, polymicrobial.

**Complications: heart failure, renal failure, stroke, non stroke embolization, intracardiac abscess, septic shock, arrhythmias.