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. 2014 Sep 4;5(5):251–257. doi: 10.1016/j.phrp.2014.08.008

Table 3.

Correlation coefficient between estimated desaturase activity and risks for metabolic syndrome.a

D6D D5D SCD-16 SCD-18
Baseline
BMI (kg/m2) 0.414*** −0.203* 0.193* −0.093
BMI z-score 0.410*** −0.209* 0.199* −0.097
Waist circumference (cm) 0.414*** −0.254** 0.209* −0.137
SBP (mmHg) 0.151 −0.137 0.153 0.068
DBP (mmHg) 0.181* −0.160 −0.031 −0.039
AST 0.279** −0.124 0.153 −0.013
ALT 0.370*** −0.164 0.155 −0.070
Total cholesterol (mg/dL) 0.214* −0.030 0.073 0.110
HDL-C (mg/dL) −0.292*** 0.082 −0.090 0.055
TG (mg/dL) 0.482*** −0.144 0.166 0.015
Glucose (mg/dL) −0.138 0.219* 0.119 0.126
Insulin (μIU/mL) 0.290** −0.195* 0.036 −0.072
HOMA-IR 0.267** −0.161 0.050 −0.054
Metabolic risk score 0.394*** −0.258** 0.200* −0.006
Follow-up
BMI (kg/m2) 0.445*** −0.279** 0.155 −0.100
BMI z-score 0.456*** −0.297*** 0.156 −0.103
Waist circumference (cm) 0.480*** −0.300*** 0.153 −0.087
SBP (mmHg) 0.340*** −0.305*** −0.017 −0.181*
DBP (mmHg) 0.203* −0.155 −0.092 −0.061
AST 0.131 −0.145 0.012 −0.092
ALT 0.306*** −0.258** 0.089 −0.116
Total cholesterol (mg/dL) 0.197* −0.092 0.091 0.123
HDL-C (mg/dL) −0.289*** 0.147 0.000 0.135
TG (mg/dL) 0.356*** −0.233** 0.090 −0.105
Glucose (mg/dL) 0.004 −0.219* −0.228** −0.208*
Insulin (μIU/mL) 0.377*** −0.261** 0.046 −0.066
HOMA-IR 0.364*** −0.278** 0.014 −0.089
Metabolic risk score 0.436*** −0.340*** 0.112 −0.107

*p < 0.05; **p < 0.01; ***p < 0.001.

ALT = alanine aminotransferase; AST = aspartate aminotransferase; BMI = body mass index; D5D = delta-5D; D6D = delta-6D; DBP = diastolic blood pressure; HDL-C = high-density lipoprotein-cholesterol; HOMA-IR = homeostasis model of assessment of insulin resistance; IU = international unit; SBP = systolic blood pressure; SCD = stearyl-CoAD; TG = triglyceride.

a

Tested by age-adjusted partial correlation analysis; data are log transformed prior to analysis.