Table 5.
Univariate and Multivariate Analyses of Clinicopathologic Data and Global Tumor Heterogeneity as Prognostic factors in EC Patients
| Analyzed Parameter | Univariate Analysis |
Multivariate Analysis |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | HR | 95% CI | P Value | |
| Histology (non-endometrioid vs endometrioid) | 4.36 | 2.61-7.29 | .0000001 | 3.68 | 2.16-6.27 | .000002 |
| Stage (III, IV vs I, II) | 1.97 | 1.62-2.39 | .0000001 | 1.58 | 1.20-2.10 | .001 |
| Grade (3 vs 1, 2) | 1.38 | 1.09-1.74 | .008 | Not significant | ||
| Metastases (present vs absent) | 3.60 | 2.23-5.81 | .0000001 | Not significant | ||
| Tumor heterogeneity (present vs absent) | 2.33 | 1.44-3.76 | .0005 | 1.71 | 1.05-2.80 | .03 |