Figure 3.

Inhibition of proteasome activities in different tissues after intraperitoneal administration of inhibitors in mice. Application of both BSc2118 (BSc) and bortezomib (Bor) yield similar inhibitory patterns of the 20S proteasome activity, which is given as relative activity of controls (abbreviated as “C”). All controls have received respectively: DMSO or 0.9% NaCl at both time points and did not show any significant differences, thus for better visibility one bar for averaged controls is shown. Mice were sacrificed either after 1 hour (grey boxes) or after 24 hours (striated boxes) post-injection, respectively. Significantly different from controls with *P < 0.05 and **P < 0.005.