. Author manuscript; available in PMC: 2014 Nov 10.

Published in final edited form as: Pharm Res. 2013 Aug 16;30(9):2232–2247. doi: 10.1007/s11095-013-1140-2

Table II.

Effect of CR on Serum Metabolic Hormones

Strain	AL/CR	Glucagon	Insulin	Leptin	Resistin
LEAN	AL	2121.7±484^a	NA	10486±2376.48^a	14355 ± 1679.5^a
	CR	388.58 ±57^b	NA	267.22 ±56.78^b	18178 ± 1672^b
OB	AL	17834 ± 3240^c	43.98 ±4.67 ^a	ND	20875 ± 1549.5^c
	CR	6735.8 ±830^d	85.26 ±24^b	ND	25365 ± 2645.83^d

Adult Lean and OB mice (n=7–10/group) were fed (ad libitum) or put on 40% reduced caloric diet for 9 weeks and average serum glucagon, insulin, leptin, and resistin concentrations (pg/ml) were determined. P <0.05 was considered statistically significant. Groups without a common letter are significantly different. ND, not detectable