Table 5.

Gene overexpression in five influenza-positive samples^*

Gene Symbol	Protein	Fold Regulation	Uncorrected P Value	FDR
AIM2	Absent in melanoma 2	2.024	0.514	0.581
AZI2	5-azacytidine induced 2	1.8315	0.003	0.077
CASP10	Caspase 10	1.9982	0.020	0.107
CASP8	Caspase 8	2.2626	0.115	0.230
CD80	CD80/B7-1	2.6996	0.980	0.980
DDX58	Retinoic acid–inducible gene-I	2.0457	0.611	0.635
HSP90AA1	Heat shock protein 90kDa α, class A member	11.8471	0.027	0.103
IFNAR1	Interferon-α/β receptor α chain	2.0322	0.156	0.270
IKBKB	Inhibitor of κ light polypeptide gene enhancer in B cells, kinase β (IκB kinase-β)	1.5971	0.025	0.111
IL12A	IL-12A	2.7291	0.367	0.434
IL12B	IL-12B	3.6472	0.358	0.444
IL15	IL-15	3.1802	0.185	0.300
IRAK1	IL-1 receptor–associated kinase 1	2.2494	0.069	0.391
IRF5	Interferon regulatory factor 3	2.0123	0.328	0.163
MAP2K1	Mitogen-activated protein kinase kinase 1 (MEK)	4.7158	0.009	0.427
MAVS	Mitochondrial antiviral signaling protein	2.355	0.010	0.129
MEFV	Pyrin	1.9129	0.041	0.094
NFKBIA	NF-κB inhibitor, α (IκBα)	2.5905	0.056	0.136
STAT1	Signal transducer and activator of transcription-1	12.3191	0.568	0.615
SUGT1	Suppressor of G2 allele of SKP1 homolog	2.2224	0.306	0.419
TBK1	TANK-binding kinase 1	3.685	0.015	0.098
TLR8	Toll-like receptor 8	2.931	0.143	0.267
TNF	Tumor necrosis factor-α	2.6749	0.263	0.403
TRAF3	TNF receptor–associated factor 3	3.1544	0.052	0.151
TRAF6	TNF receptor–associated factor 6	2.2136	0.112	0.244

Definition of abbreviations: FDR = false discovery rate; TNF = tumor necrosis factor.

^*Compared with 22 virus-negative samples.