Table 3.
Comparison of OARs’ doses calculated from PVP, HAP and non-enhanced CTs
| Dp | Da | Dn | P(p,a,n)* | (Dn-Dp)/Dn (%) | P(p,n)# | (Dn-Da)/Dn (%) | P(a,n)# | (Da-Dp)/Dn (%) | P(p,a)# | |
|---|---|---|---|---|---|---|---|---|---|---|
|
3D-CRT |
|
|
|
|
|
|
|
|
|
|
| Liver V21 (%) |
12.77 ± 11.45 |
12.87 ± 11.53 |
12.94 ± 11.55 |
0.000 |
1.70 ± 1.50 |
0.000 |
0.90 ± 1.20 |
0.000 |
0.80 ± 0.85 |
0.000 |
| Liver Dmean (Gy) |
8.52 ± 5.00 |
8.57 ± 5.03 |
8.61 ± 5.04 |
0.000 |
1.02 ± 0.73 |
0.000 |
0.51 ± 0.64 |
0.000 |
0.52 ± 0.47 |
0.000 |
| Right kidney D2%(Gy) |
13.59 ± 14.36 |
13.60 ± 14.35 |
13.69 ± 14.48 |
0.000 |
0.56 ± 1.29 |
0.000 |
0.33 ± 1.10 |
0.001 |
0.23 ± 0.58 |
0.140 |
| Right kidney Dmean (Gy) |
2.87 ± 3.47 |
2.87 ± 3.47 |
2.89 ± 3.50 |
0.201 |
-0.09 ± 1.01 |
- |
0.18 ± 0.81 |
- |
-0.27 ± 0.53 |
- |
| Bowl D2% (Gy) |
12.83 ± 8.63 |
12.84 ± 8.65 |
12.86 ± 8.72 |
0.040 |
-0.31 ± 2.50 |
0.254 |
-0.13 ± 2.27 |
0.074 |
-0.18 ± 1.13 |
0.268 |
| Stomach D2% (Gy) |
16.42 ± 7.62 |
16.54 ± 7.66 |
16.65 ± 7.69 |
0.000 |
1.45 ± 2.33 |
0.003 |
0.71 ± 1.40 |
0.004 |
0.74 ± 1.31 |
0.001 |
| Spinal cord D2% (Gy) |
11.28 ± 6.79 |
11.31 ± 6.79 |
11.36 ± 6.81 |
0.006 |
0.73 ± 1.38 |
0.000 |
0.46 ± 0.88 |
0.004 |
0.27 ± 1.06 |
0.234 |
|
IMRT |
|
|
|
|
|
|
|
|
|
|
| Liver V21 (%) |
25.31 ± 6.90 |
25.35 ± 6.89 |
25.39 ± 6.87 |
0.040 |
0.38 ± 0.87 |
0.046 |
0.19 ± 0.68 |
0.338 |
0.19 ± 0.43 |
0.026 |
| Liver Dmean (Gy) |
10.00 ± 4.95 |
10.05 ± 4.99 |
10.09 ± 4.99 |
0.000 |
0.97 ± 0.77 |
0.000 |
0.49 ± 0.74 |
0.000 |
0.48 ± 0.46 |
0.000 |
| Right kidney D2% (Gy) |
14.71 ± 14.88 |
14.71 ± 14.89 |
14.82 ± 15.02 |
0.003 |
0.32 ± 1.22 |
0.002 |
0.30 ± 1.21 |
0.006 |
0.01 ± 0.50 |
0.050 |
| Right kidney Dmean (Gy) |
3.04 ± 3.12 |
3.03 ± 3.12 |
3.06 ± 3.15 |
0.090 |
0.02 ± 1.00 |
- |
0.29 ± 0.84 |
- |
-0.27 ± 0.54 |
- |
| Bowl D2% (Gy) |
10.99 ± 6.88 |
11.02 ± 6.90 |
11.09 ± 6.93 |
0.000 |
0.90 ± 0.86 |
0.000 |
0.65 ± 0.88 |
0.002 |
0.26 ± 0.69 |
0.178 |
| Stomach D2% (Gy) |
11.73 ± 6.99 |
11.80 ± 7.03 |
11.85 ± 7.07 |
0.000 |
0.89 ± 1.90 |
0.012 |
0.39 ± 1.23 |
0.008 |
0.50 ± 1.28 |
0.002 |
| Spinal cord D2% (Gy) |
9.09 ± 4.50 |
9.12 ± 4.49 |
9.17 ± 4.50 |
0.003 |
0.99 ± 1.64 |
0.003 |
0.57 ± 1.13 |
0.001 |
0.42 ± 0.95 |
0.195 |
|
VMAT |
|
|
|
|
|
|
|
|
|
|
| Liver V21 (%) |
20.71 ± 7.27 |
20.75 ± 7.27 |
20.77 ± 7.26 |
0.017 |
0.35 ± 0.71 |
0.018 |
0.14 ± 0.47 |
0.355 |
0.21 ± 0.34 |
0.005 |
| Liver Dmean (Gy) |
10.10 ± 5.24 |
10.16 ± 5.28 |
10.20 ± 5.29 |
0.000 |
0.97 ± 0.67 |
0.000 |
0.45 ± 0.59 |
0.000 |
0.52 ± 0.43 |
0.000 |
| Right kidney D2% (Gy) |
14.30 ± 14.80 |
14.33 ± 14.83 |
14.41 ± 14.87 |
0.000 |
0.68 ± 1.08 |
0.000 |
0.38 ± 0.89 |
0.000 |
0.31 ± 0.48 |
0.000 |
| Right kidney Dmean (Gy) |
3.34 ± 3.55 |
3.34 ± 3.55 |
3.36 ± 3.56 |
0.187 |
-0.03 ± 1.03 |
- |
0.14 ± 0.76 |
- |
-0.17 ± 0.41 |
- |
| Bowl D2% (Gy) |
11.87 ± 7.28 |
11.90 ± 7.32 |
11.98 ± 7.35 |
0.000 |
0.95 ± 0.87 |
0.000 |
0.81 ± 1.02 |
0.001 |
0.14 ± 0.94 |
0.206 |
| Stomach D2% (Gy) |
11.53 ± 8.30 |
11.65 ± 8.47 |
11.65 ± 8.40 |
0.000 |
0.78 ± 1.60 |
0.001 |
0.08 ± 1.95 |
0.031 |
0.70 ± 1.12 |
0.000 |
| Spinal cord D2% (Gy) | 9.92 ± 3.79 | 9.93 ± 3.79 | 9.95 ± 3.80 | 0.013 | 0.24 ± 1.18 | 0.010 | 0.21 ± 0.56 | 0.031 | 0.04 ± 0.77 | 0.081 |
Abbrevations: V21, the percentage liver volume received more than 21 Gy; Dmean, the mean dose; D2%, the minimum absorbed dose that covers 2% of the volume of a certain OAR. The others as in Table 2. *, Friedman test; #, Wilcoxon signed ranks test.