Table 4.
Difference in Changes over Time in Lung Function between Control Subjects and Patients with Asthma in Response to Bariatric Surgery
| Control Subjects Mean Difference (95% CI) | Patients with Asthma Mean Difference (95% CI) | P Value* | Adjusted P Value† | |
|---|---|---|---|---|
| FEV1 | 5.2 (0.9 to 9.4) | 7.4 (2.5 to 12.2) | 0.49 | 0.29 |
| FVC | 4.9 (−0.1 to 9.9) | 5.1 (−0.6 to 10.8) | 0.96 | 0.83 |
| FEV1/FVC | 0.3 (−4.3 to 4.8) | 2.5 (−2.7 to 7.7) | 0.50 | 0.51 |
| TLC | 17.1 (4.6 to 29.7) | 1.5 (−11.4 to 14.3) | 0.08 | 0.16 |
| IC | −2.7 (−20.6 to 15.2) | −13.2 (−31.6 to 5.1) | 0.4 | 0.64 |
| SVC | 3.1 (−2.9 to 9.1) | 3.0 (−3.0 to 9.0) | 0.98 | 0.95 |
| FRC | 15.8 (0.3 to 31.3) | 1.2 (−14.8 to 17.2) | 0.18 | 0.19 |
| ERV | 19.2 (3.2 to 35.2) | 12.6 (−3.7 to 29.0) | 0.55 | 0.37 |
| RV | 30.8 (−1.5 to 63.1) | −12.8 (−46.2 to 20.6) | 0.06 | 0.07 |
| RV/TLC | 12.2 (−12.4 to 36.9) | −22.0 (−47.5 to 3.4) | 0.06 | 0.06 |
| DlCO | −0.2 (−8.6 to 8.2) | −2.9 (−12.2 to 6.4) | 0.65 | 0.64 |
Definition of abbreviations: CI = confidence interval; DlCO = diffusing capacity of carbon monoxide; ERV = expiratory reserve volume; IC = inspiratory capacity; RV = residual volume; SVC = slow vital capacity.
Values are % predicted mean difference and 95% CI.
*
P values shown are for group × visit interaction results from mixed model repeated measures analyses of variance.
†
Adjusted P value with body mass index as a covariate in the mixed model repeated measures analysis of variance.