Fig. 1.

Induction of WWOX expression early after DNA damage stimuli. (A) Real-time PCR analysis of WWOX, FHIT, and MAF in MCF7 after ionizing radiation treatment for the indicated time points. (B–E) Immunoblot blot analyses of WWOX levels in (B and C) MCF7 and (D and E) early-passage MEFs after treatment with ionizing radiation (10 Gy) or NCS (200 ng/mL) for different time points. Equal loading was confirmed by blotting with α-GAPDH–specific antibody. Fold change of WWOX expression upon DNA damage relative to untreated cells is shown below each blot.