Fig. 4.

Alternative splicing upon AGO1 knockdown. (Left) The genomic loci for three genes, CAP2, CCDC125, and PIP5K1A, with intragenic active enhancers (blue rectangles) binding AGO1 (red profiles) and containing an alternative splicing event (black track) that changes inclusion upon knockdown of AGO1. (Right) The inclusion levels (y axis) for the two replicates in control (green bars) and the knockdown of AGO1 (blue bars). Active enhancers and regulated events were determined as specified in Methods.