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. 2014 Nov 10;8:129. doi: 10.3389/fnana.2014.00129

Figure 3.

Figure 3

Network assembly process. (A) Standardized 3D reference frame of rat vibrissal cortex, with 3D organization of horizontal (i.e., barrel columns) and vertical (i.e., layers) structures. Every point in this brain region can be assigned to a barrel column and a cortical layer with 50 μm precision. (B) 3D distribution of 530,000 somata of 10 excitatory and 5 inhibitory cell types. (C) Replacement of somata with cell type-specific 3D dendrite morphologies. (D) Replacement of somata with cell type-specific 3D axon morphologies. Shown here: Thalamocortical axons from VPM (black), intracortical axons of inhibitory interneurons (green). (E) Top: Close-up view of inset in (B). Center: Close-up view of inset in (C), showing the dendrites of a single L4 spiny stellate (L4ss) neuron (red) next to all dendrites from all cell types in the neighboring barrel column. Bottom: Close-up view of inset in (D), showing a single thalamocortical VPM axon (blue) next to all axons from two cell types in the neighboring barrel column.