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. Author manuscript; available in PMC: 2014 Nov 10.
Published in final edited form as: BJU Int. 2011 Nov 11;110(3):338–343. doi: 10.1111/j.1464-410X.2011.10750.x

TABLE 3.

Cumulative risk of having unfavourable pathological characteristics associated with carrying any one or any two to three risk alleles (rs1447295 [8q24], rs1571801 [9q33.2] and rs 11228565 [11q13]) in men who would have been eligible for an AS protocol

Number of prostate cancer risk alleles carried Favourable pathological characteristics, % (n) Unfavourable pathological characteristics, % (n) Odds ratio 95% CI P
None 47.6 (79) 22.5 (11) Reference Reference -
Any 1 44.6 (74) 51.0 (25) 2.4 1.2-5.3 0.03
Any 2-3 7.8 (13) 26.5 (13) 7.2 2.7-19.4 0.0001