A proposed model for GSD1 modulation of PD permeability. GSD1 encodes a PM protein, remorin, which is colocalized in PD with PD-specific proteins: GPI-anchored callose binding protein PDCB1, which is located at the neck region of PD (Simpson et al., 2009); and PD-located proteins PDLP1 and PDLP5 (Thomas et al., 2008; Lee et al., 2011). GSD1 interacts with OsACT1, which is associated with the desmotubule structure in PD. GSD1 may play a role in connecting the desmotubule and PM in the PD neck regions of companion cells, modulating the PD aperture through its expression levels and PM anchor. CW, Cell wall; DT, desmotubule; ER, endoplasmic reticulum.