Table 1.
Clinical assessments and laboratory findings in obese, preobese, and control groups
| Parameters | Control group (n=40) | Preobese group (n=40) | Obese group (n=40) |
|---|---|---|---|
| Age (years) | 34.79±11.18 | 31.65±11.54 | 36.26±9.68 |
| BMI (kg/m2) | 23.35±1.04 | 27.86±1.28a,*** | 34.47±3.27b,***,c,*** |
| WHR (Gw/Gh) | 0.81±0.04 | 0.86±0.07a,** | 0.86±0.07b,** |
| BDI | 8.34±2.00 | 10.62±5.02 | 15.05±7.75b,***,c,** |
| BAI | 5.00 (3.00–10.00) | 7 (1.00–20.00) | 8 (0–39) |
| MMSE | 27 (22.00–30.00) | 26.00 (24–30) | 26.50 (20–30) |
| BDNF (pg/mL) | 119.75 (85.00–188.58) | 115.64 (55.68–165.00) | 95.75 (42.84–158.06)b,** |
| Glucose (mg/dL) | 93 (68.00–124.00) | 91 (82.00–166.00) | 99.00 (83.00–132.00)c,** |
| Trig (mg/dL) | 108 (35.00–339.00) | 95 (40–292) | 122.00 (45.00–295.00) |
| T chol (mg/dL) | 195 (145.00–265.00) | 187 (134–306) | 192.00 (149.00–265.00) |
| HDL (mg/dL) | 45 (26.00–79.00) | 53 (25–95) | 50 (34–78) |
| LDL (mg/dL) | 114 (70.00–199.00) | 102 (65–192) | 114.5 (62–191) |
| TSH (mIU/mL) | 1.87 (0.94–4.28) | 2.39 (0.03–5.18) | 2.34 (0.71–6.56) |
| FT3 (pg/mL) | 3.44 (2.14–4.29) | 3.22 (2.82–4.19) | 3.19 (2.64–4.04)b,* |
| FT4 (ng/dL) | 1.25 (0.85–1.48) | 1.18 (1.00–1.42) | 1.17 (0.88–1.39) |
| Vit B12 (pg/mL) | 336.10 (154.9–740.50) | 306 (174.8–759.60) | 309.7 (133.7–465.2) |
| Folic acid (ng/mL) | 7.63 (4.60–15.45) | 7.79 (5.14–17.17) | 8.94 (5–17.01) |
| Insulin (μlU/mL) | 7.75 (3.47–13.48) | 11 (5.98–23.19)a,*** | 12.19 (6.5–29.77)b,*** |
| CRP (mg/L) | 2.20 (0.20–8.00) | 3 (0.6–12.6) | 3.75 (1–14.5)b,** |
| HbA1c (%) | 5.20 (4.10–6.30) | 5.3 (3.0–7.30) | 5.5 (5–6)b,* |
| HOMA | 1.24 (0.62–2.49) | 2.32 (1.21–5.98)a,*** | 3 (1.48–7.06)b,*** |
Notes:
P<00.05
P<0.01
P<0.001
preobese vs control
obese vs control
obese vs preobese. Normally distributed data are presented as mean ± SD, non-normally distributed data are presented as median (minimum-maximum).
Abbreviations: BAI, Beck Anxiety Inventory; BDI, Beck Depression Inventory; BDNF, brain-derived neurotrophic factor; BMI, body mass index; CRP, C-reactive protein; Gw/Gh, waist girth/hip girth; FT3, free triiodothyronine; FT4, free thyroxine; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; HOMA, homeostatic model assessment; LDL, low-density lipoprotein; MMSE, mini-mental state examination; SD, standard deviation; T chol, total cholesterol; Trig, triglycerides; TSH, thyroid-stimulating hormone; Vit, vitamin; WHR, waist-to-hip ratio.