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. 2014 Nov 10;9(11):e111909. doi: 10.1371/journal.pone.0111909

Table 4. Regression coefficients of log-transformed blood cadmium levels with each components the Framingham estimate of 10-year CHD risk among Korean men.

Dependent variables		beta	SE	p value	Dependent variables		beta	SE	p value
20≤Age<35					50≤Age<55
	Age	0.702	0.215	0.001		Age	0.242	0.152	0.114
	SBP^*	2.539	1.276	0.047		SBP^*	7.999	1.958	<0.001
	Total cholesterol^*	0.889	2.615	0.734		Total cholesterol^*	−3.593	4.964	0.470
	HDL cholesterol^*	1.258	1.027	0.221		HDL cholesterol^*	1.216	1.316	0.356
	Urinary cotinine	832.616	80.250	<0.001		Urinary cotinine	1010.182	128.276	<0.001
35≤Age<40					55≤Age<60
	Age	−0.069	0.148	0.643		Age	−0.013	0.146	0.932
	SBP^*	1.972	1.553	0.205		SBP^*	3.650	1.940	0.061
	Total cholesterol^*	−2.082	3.439	0.545		Total cholesterol^*	2.091	5.408	0.699
	HDL cholesterol^*	0.145	1.334	0.914		HDL cholesterol^*	1.765	1.443	0.223
	Urinary cotinine	732.704	77.385	<0.001		Urinary cotinine	809.187	112.660	<0.001
40≤Age<45					60≤Age<65
	Age	−0.113	0.180	0.528		Age	0.189	0.214	0.378
	SBP^*	7.085	3.211	0.028		SBP^*	7.218	2.464	0.004
	Total cholesterol^*	6.893	6.363	0.280		Total cholesterol^*	8.403	5.785	0.148
	HDL cholesterol^*	2.714	1.870	0.148		HDL cholesterol^*	1.897	1.687	0.262
	Urinary cotinine	1012.800	117.604	<0.001		Urinary cotinine	790.009	126.085	<0.001
45≤Age<50
	Age	0.384	0.145	0.009
	SBP^*	3.893	2.308	0.093
	Total cholesterol^*	4.484	4.897	0.361
	HDL cholesterol^*	−0.499	1.466	0.734
	Urinary cotinine	971.939	126.092	<0.001

Results were estimated with study weights.

beta: regression coefficients; SE: standard error; SBP: systolic blood pressure; HDL: high density lipoprotein.

Units: SBP (mmHg); Age (year); Total cholesterol (mg/dL); HDL cholesterol (mg/dL); Urinary cotinine (ng/mL).

All regression analyses were adjusted for survey year in multivariate regression analysis.

*: adjusted for survey years, age and urinary cotinine in multivariate regression analysis.