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. 2014 Nov 10;9(11):e110817. doi: 10.1371/journal.pone.0110817

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© 2014 Camilo et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Respiratory system elastance (Ers) throughout ventilation protocols. Red points are minute-averaged values of Ers and its fitted line (blue line). B. Slope of Ers calculated by angular coefficient of the groups: VCV_E (volume-controlled mode and PEEP_minErs; n = 6), VCV_E+2 (volume-controlled mode and PEEP_minErs plus 2 cmH₂O; n = 6), VCV_E-2 (volume-controlled mode and PEEP_minErs minus 2 cmH₂O; n = 6), VV_E (variable ventilation and PEEP_minErs; n = 6), VV_E+2 (variable ventilation and PEEP_minErs plus 2 cmH₂O; n = 5), VV_E-2 (variable ventilation and PEEP_minErs minus 2 cmH₂O; n = 6). Effect of ventilator mode, PEEP and interaction were tested with two-way ANOVA followed by Tukey post-hoc. Time effect was tested by generalized linear model. Statistical significance was accepted at p<0.05. *p<0.05.