Figure 5. Diffuse alveolar damage score.

Score of 0–9 to alveolar edema (A), interstitial edema (B), hemorrhage (C), inflammation (D), atelectasis (E) and the cumulative total score in the groups: VCV_E (volume-controlled mode and PEEP_minErs; n = 6), VCV_E+2 (volume-controlled mode and PEEP_minErs plus 2 cmH₂O; n = 6), VCV_E-2 (volume-controlled mode and PEEP_minErs minus 2 cmH₂O; n = 6), VV_E (variable ventilation and PEEP_minErs; n = 6), VV_E+2 (variable ventilation and PEEP_minErs plus 2 cmH₂O; n = 5), VV_E-2 (variable ventilation and PEEP_minErs minus 2 cmH₂O; n = 6). Red lines represent mean values. Ventilatory mode and PEEP effects were tested with two-way ANOVA followed by Tukey post hoc. T-test was used to detect differences between ventilated and non-ventilated groups and then correction by multiple comparison. Statistical significance was accepted at p<0.05. *p<0.05.