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Histopathology of CD8+/+ and CD8−/− mice
| Group | 2-OA–BSA | α-GalCer | Portal inflammation | Fibrosis |
|---|---|---|---|---|
| CD8+/+ | – | – | 0/5 (0%) | 0/5 (0%) |
| CD8+/+ | + | – | 4/6 (66·7%) | 1/6 (16·67%) |
| CD8+/+ | + | + | 10/11 (90·91%) | 10/11 (90·91%) |
| CD8−/− | – | – | 0/5 (0%) | 0/5 (%) |
| CD8−/− | + | – | 6/8 (75%) | 0/8 (0%) |
| CD8−/− | + | + | 14/14 (100%) | 14/14 (100%) |
α-GalCer = α-galactosylceramide; 2-OA–BSA/PBS = 2-octynoic acid conjugated bovine serum albumin.
