Fig. 1.

Lymphocyte subpopulations expressing ectonucleotidases. (a) Co-expression of CD39 and CD73 on CD4⁺ T cells and CD19⁺ B cells in peripheral blood lymphocytes obtained from a representative normal donor (NC). The gates were set based on side- and forward-scatter. (b) Box-plots showing the frequency of CD4⁺CD73⁺CD39(–) T cells and CD4⁺CD39⁺CD73(–) regulatory T cells (T_reg) in the peripheral circulation of 29 NC. Box-plots show medians and quartiles for 25 and 75% as boxes and values for 0% and 100% as whiskers. (c) The percentages of CD4⁺CD39⁺ T_reg and CD4⁺CD73⁺ T cells in the peripheral blood of NC do not correlate with each other.