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. 2014 Nov 10;9(11):e112672. doi: 10.1371/journal.pone.0112672

Figure 7. Effect of Adaprev and G6P on actin cytoskelaton of rat flexor tendon fibroblasts.

Figure 7

Rat flexor tendons were grown in DMEM containing 10% Fetal Bovine Serum (FBS) and then transferred to media without FBS before either having Adaprev or 600 mM G6P added to the media. Non treatment controls were maintained in DMEM without serum. Cells were maintained under the above conditions for up to 60 minutes and photographed at various times to record the cellular effects. At 15 minutes the cells in both groups show “stress shielding” of the actin cytoskeleton then at 60 minutes similar crenation effects upon both the Adaprev and G6P treated cells were observed.