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. 2014 Nov;148(5):2335–2344. doi: 10.1016/j.jtcvs.2014.04.037

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© 2014 by The American Association for Thoracic Surgery. All rights reserved.

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A high dose of theophylline improved lung function after deflation. After equilibration, the lungs were subjected to deflation/reinflation in the absence of theophylline (D/R) or in the presence of theophylline (D/R+theophylline 0.083 or 3 mM). Dynamic compliance and vascular resistance were measured throughout the experiment. Data are expressed as the mean ± standard error of the mean of 6 lungs per group. *P < .05 compared with no treatment (area under the curve analysis and 1-way analysis of variance with Dunnett's test).