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| Level | Docetaxel (mg/m2) | Indoximod (mg) | No. of Patients Treated | No. of Cycles Administered | Cycles per Patient (median) | Dose limiting toxicities |
|---|---|---|---|---|---|---|
| 1 | 60 | 300 | 7 | 28 | 3 | Grade 3 dehydration |
| 2 | 60 | 600 | 6 | 35 | 3 | Grade 5 colitis |
| 3 | 60 | 1000 | 6 | 39 | 3 | |
| 4 | 60 | 2000 | 2 | 2 | 1 | Grade 3 hypotension,mucositis |
| 5 | 75 | 1200 | 6 | 16 | 2 |
