Table 1. Relationship of the Expression of ISG15 and Clinicopathological Feature of HCC.

Parameter	Groups	Number of Patient	ISG15 Relative Expression	P
Age(yr)	≥50	19	0.92±0.14	0.764
	<50	31	0.84±0.09
Gender	Male	44	0.85±0.08	0.456
	Female	6	0.86±0.22
HBV infection	Postive	46	0.89±0.08	0.555
	Negative	4	1.07±0.38
AFP(ng/ml)	≥400	27	0.87±0.11	0.394
	<400	23	0.93±0.12
Tumor size(cm)	≥5	29	0.88±0.12	0.680
	<5	21	0.84±0.09
Tumor number	Single	39	0.86±0.09	0.210
	Multiple	11	1.22±0.13
Differentiation	Moderate to well	33	0.54±0.06	<0.001*
	Poor	17	1.34±0.20
Portal vein tumor thrombus	Positive	3	1.01±0.40	0.685
	Negative	47	0.86±0.08
Metastasis	Positive	22	1.12±0.10	0.001*
	Negative	28	0.68±0.11